Stroke affects more than just the physical

Stroke affects more than just the physical

First published on ScienceDaily

A new study looks at what problems affect people most after a stroke and it provides a broader picture than what some may usually expect to see. Stroke affects more than just physical functioning, according to a study is published the March 28, 2018, online issue of Neurology®, the medical journal of the American Academy of Neurology.

“After a stroke, people who have only mild disability can often have ‘hidden’ problems that can really affect their quality of life,” said study author Irene L. Katzan, MD, MS, of the Cleveland Clinic in Ohio and a member of the American Academy of Neurology. “And for people with more disability, what bothers them the most? Problems with sleep? Depression? Fatigue? Not many studies have asked people how they feel about these problems, and we doctors have often focused just on physical disability or whether they have another stroke.” (more…)

Stroke affects more than just the physical

Heart disease, stroke less widespread among foreign-born vs. US-born adults

First published on ScienceDaily

Foreign-born adults living in the United States had a lower prevalence of coronary heart disease and stroke than U.S.-born adults in nationally representative data spanning 2006-2014, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

Researchers from the Centers for Disease Control and Prevention compared the prevalence of coronary heart disease and stroke among U.S. adults by birthplace. The proportion of adults living in the United States who were born elsewhere has almost tripled from about 9.6 million in 1970 to 40 million in 2010. (more…)

Stroke affects more than just the physical

Detection of transcranial direct current stimulation deep in the living human brain

Published first on ScienceDaily

A defining characteristic of stroke is the loss of motor control due to structural damage in specific brain areas. In fact, motor impairments (or deficits) are the number one complication after stroke. Losing the ability to carry out basic bodily functions, such as speaking, walking and swallowing, can be devastating for stroke survivors. Unfortunately, there are few effective recovery options beyond physical and occupational therapy to stimulate brain re-learning. While many researchers have tried to identify effective new therapies to mitigate motor function impairment and enhance quality-of-life, discoveries have been lacking. (more…)

Stroke affects more than just the physical

Vagus nerve stimulation boosts post-stroke motor skill recovery

Published first on ScienceDaily

Researchers at The University of Texas at Dallas have demonstrated a method to accelerate motor skill recovery after a stroke by helping the brain reorganize itself more quickly.

In a preclinical study, the scientists paired vagus nerve stimulation (VNS) with a physical therapy task aimed at improving the function of an upper limb in rodents. The results showed a doubled long-term recovery rate relative to current therapy methods, not only in the targeted task but also in similar muscle movements that were not specifically rehabbed. Their work was recently published in the journal Stroke. (more…)

Stroke affects more than just the physical

Portable device detects severe stroke in seconds with 92 percent accuracy

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A new device worn like a visor can detect emergent large-vessel occlusion in patients with suspected stroke with 92 percent accuracy, report clinical investigators at the Medical University of South Carolina (MUSC), Mount Sinai, the University of Tennessee Health Sciences Center and elsewhere in an article published online on March 6, 2018, in the Journal of Neurointerventional Surgery. Patients with large-vessel occlusions can then be routed to a Comprehensive Stroke Center with endovascular capabilities. In contrast, a standard physical examination achieved only 40 to 89 percent accuracy in identifying patients with large-vessel occlusion who could benefit from endovascular therapy. (more…)

Stroke affects more than just the physical

Drug reduces inflammation in stroke patients

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An anti-inflammatory drug given to patients in the early stages of a stroke has been shown by researchers at The University of Manchester and Salford Royal NHS Foundation Trust to reduce harmful inflammation.
The drug, Kineret©, licenced for treating rheumatoid arthritis, was given as a small injection just under the skin without giving the patients any identifiable adverse reactions.

It is one of biologic agents transforming treatment in a range of illnesses. The protein Interleukin-1 (IL-1) is part of the body’s defences and naturally produced to combat a range of illnesses. However, scientists at the University of Manchester have previously shown IL-1 increases inflammation and brain injury following a stroke. (more…)

A challenge for policy makers and a framework for tackling the rising burden of stroke in Europe

A challenge for policy makers and a framework for tackling the rising burden of stroke in Europe

The Stroke Action Plan for Europe 2018 – 2030

A challenge for policy makers and a framework for tackling the rising burden of stroke in Europe

Leaders of the European stroke community met today in Munich to develop the ESO / SAFE Stroke Action Plan for Europe 2018-2030, including leading academics, stroke survivors and caregivers, doctors, nurses, physiotherapists, occupational therapists and representatives from stroke organisations and the World Health Organisation. It creates an aspirational framework to drive healthcare policy, research priorities, local stroke management and patient-focussed care to meet the need demonstrated in the ESO / SAFE Burden of Stroke report, with €45 billion direct and indirect healthcare costs each year, a 34% increase in strokes by the year 2035 due to the ageing population, and huge variations in the level of stroke care available across Europe. (more…)

PRESTIGE AF: International project launches to prevent stroke in patients with brain bleeding

PRESTIGE AF: International project launches to prevent stroke in patients with brain bleeding

A new multi-million Euro initiative funded by the European Commission has been set up to help prevent stroke in patients with existing conditions.

The €6.9m project is aimed at patients with atrial fibrillation (AF), a common heart condition which causes irregular and abnormally fast heartbeat, who have previously had a stroke caused by bleeding in the brain (termed intracerebral haemorrhage or ICH). The Prevention of Stroke in intracerebral hemorrhage survivor with Atrial Fibrillation (PRESTIGE-AF) brings together scientists and clinicians across Europe with the goal of reducing the risk of further stroke in this group of patients. (more…)

Stroke affects more than just the physical

Worldwide study triples number of known genetic risk factors for stroke

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A landmark international study of DNA samples from 520,000 individuals worldwide — including 67,000 affected individuals — identified 22 new genetic risk factors for stroke. Sudha Seshadri, M.D., of UT Health San Antonio, is senior co-author of this largest genetic study of stroke to date. Nature Genetics published the results online March 12 2018.

Previously, only 10 genetic risk factors had been identified for stroke.

Dr. Seshadri, founding director of the Glenn Biggs Institute for Alzheimer’s & Neurodegenerative Diseases at UT Health San Antonio and holder of the university’s Robert Barker Distinguished University Chair, said the identification of genetic regions that are strongly correlated to stroke will increase potential targets for stroke drug development. (more…)

Stroke affects more than just the physical

Dengue fever linked to increased risk of stroke

Published first on ScienceDaily

A new study has found that people with dengue fever have a higher risk of stroke, especially in the first 2 months following infection. The study is published in CMAJ (Canadian Medical Association Journal).

“Clinicians in dengue-endemic areas should be aware of this association, especially for patients with dengue who have neurologic deficits or for patients with stroke who have unexplained fever,” writes Dr. Chia-Hung Kao, Department of Nuclear Medicine and PET Center, China Medical University Hospital, Taichung, Taiwan, with coauthors.

Dengue is a mosquito-borne viral infection that infects at least 100 million people every year around the world, with about 4 billion people at risk of the illness, which includes dengue hemorrhagic fever that can lead to spontaneous bleeding, organ failure and death. It is found in many countries in South and Southeast Asia, Africa, South America, the Caribbean, in the United States and more. (more…)