After having taken many regulatory hurdles, the trial PRECIOUS is now coming up to speed!
PRECIOUS has full approval in Estonia, Germany, Hungary, Italy, Norway, the Netherlands, and the UK. Poland and Greece are almost there! A total number of 16 sites across Europe have been initiated and we expect this number to increase to 80 by the end of this year. (more…)
Your cognitive capacity is significantly reduced when your smartphone is within reach — even if it’s off. That’s the takeaway finding from a new study from the McCombs School of Business at The University of Texas at Austin.
McCombs Assistant Professor Adrian Ward and co-authors conducted experiments with nearly 800 smartphone users in an attempt to measure, for the first time, how well people can complete tasks when they have their smartphones nearby even when they’re not using them. (more…)
Using musical cues to learn a physical task significantly develops an important part of the brain, according to a new study.
People who practiced a basic movement task to music showed increased structural connectivity between the regions of the brain that process sound and control movement.
The findings focus on white matter pathways — the wiring that enables brain cells to communicate with each other. (more…)
The Experts Statement Document
Tallinn, Estonia, July, 6 2017
Inequalities in stroke risk and stroke provision across Europe should be of great concern to European policy makers, especially considering the predicted increase in the number of people having a stroke in the future. Stroke is a leading cause of disability and mortality among adults.
Stroke is the second most common cause of death and the third most common cause of loss of disability-adjusted life years (DALYs) worldwide. Two types of stroke can be distinguished: 80% ischaemic, most often caused by an occlusion of a cerebral artery. The remaining 20% are haemorrhagic, most often caused by a rupture of an artery. Every year, 1,3 million Europeans have a first stroke. 20 – 35% of these patients succumb within the first month, and around one third remain dependent on the help of others. Even in patients who survive a stroke with minor disabilities, quality of life is often substantially and irreversibly impaired.
From left to the right: Üllar Kaljumäe, Chief Medical Officer of Estonia; Jelena Misita, SAFE; Prof. Janika Kõrv, University of Tartu, Estonia; Prof. Kaste Markku, University of Helsinki, Finland; Prof. Toomas Asser, University of Tartu, Estonia; Vinciane Quoidbach, EBC
Across Europe, stroke accounts over 1 million deaths each year. Most of these victims are elderly patients. However, death rates vary substantially between countries and are more than three times higher in central and eastern Europe than in northern, southern and western Europe.10 Although early stroke mortality rates have decreased over the past two decades, the burden of stroke in terms of the absolute number of people affected, related deaths and DALYs lost are increasing, with most of the burden in low-income and middle-income European countries. The quality of stroke care varies widely throughout the EU, mirroring death rates ranging from approximately 6% to nearly 20%. Other disparities include gender imbalances and the number of hospital discharges and lengths of stay for patients treated for CVD. Across Europe, it has been estimated that only 30% of patients are treated in a Stroke Unit, which means that 70% of patients with acute stroke are withheld care that is of proven benefit.
There is a need to reduce the burden of stroke throughout the EU through better evidenced based prevention and care.
In 2006, co-sponsored by the WHO Regional Office for Europe, the second Helsingborg Declaration set new targets for stroke management and care: “continuum of care from organized stroke units in the acute phase to appropriate rehabilitation and secondary prevention measures.” The specific goals for 2015 had been that: > 85% of patients should survive the first month after stroke, that 70% of survivors should be independent at 3 months and that all patients with acute stroke, potentially eligible for acute, specific treatment, should be transferred to hospitals with adequate capacity and expertise to administer treatments defined as a Stroke Unit or Stroke dedicated areas. A 3rd European Action plan is currently drafted to verify the achievement of these goals and set goals for 2030.
Effective stroke care planning and adequate resource allocation across Europe are crucial to address primary and secondary prevention and timely intervention as well as equal access and quality of care for all patients. Indeed, care for stroke patients begins before a stroke has happened with the identification of people at risk of stroke, modification of lifestyle patterns, and treatment of vascular risk factors in the primary care setting. Stroke care strategies should then focus on optimal treatment of acute stroke in an acute stroke unit and on avoiding further vascular events, delivered through a comprehensive stroke service quality standards. Every step of the patient care pathway from symptom onset to the start of treatment within the hospital should be optimized in order to save time and to offer all medical opportunities including thrombolysis and thrombectomy for improved survival rates, reduced complications and disability. During and after the acute phase, targeted rehabilitation is needed for better recovery and quality of life.
Our aim is to prevent stroke from happening in the first place and improve the quality of life of the stroke patients and their carers. To achieve these goals, every national stakeholder when assessing, planning and implementing their national stroke strategy should consider the following recommendations:
Primary and secondary stroke prevention is crucial and should be available to all of the people at risk.
Primary care is increasingly taking on a greater role in both, the assessment and the long-term care of stroke patients – in order to ensure an efficient collaboration between primary care physicians and specialist care, incentives should be created and expertise should be built in order to improve long-term outcome of stroke patients.
The Stroke Units network needs to be established in all European countries to ensure fast admission of all stroke patients. These Stroke Units have to be certified by qualified national authorities either the international professional bodies. A Comprehensive Stroke Centre needs to be established in order to foster access to reperfusion therapies. Furthermore, specific clinical services and targeted training programmes need to be developed.
Access to evidenced-based treatments of acute stroke and prevention strategies need to be guaranteed for all patients.
Effective evidence-based treatments for acute stroke care and for secondary prevention shall be available to all patients.
National evaluations based on audits or quality registries are needed to provide feedback to medical professionals and national decision makers for the implementation of evidence-based medicine in clinical practice.
Access to timely and personalised rehabilitation should be made available to all stroke patients, starting from acute Stroke Units in a continuum of care to rehabilitation service based on patient needs, including early supported discharge, comprehensive inpatient rehabilitation unit and long-term facilities for patients having stroke sequels.
Clinical quality registries are essential to analyze the development of stroke outcome, using the data to provide feedback to healthcare professionals and converge evidence to decision makers.
Stroke research is grossly underfunded. Funding for stroke research needs to be increased proportionally to the burden of disease.
The psychological and emotional impacts of stroke are very often ignored. Therefore, we call on all European countries to consider implementing patient psychological and behavioral support programs after stroke, ensuring a holistic approach to tackling “life after stroke” issues.
Stroke support organisations have important role in helping patients and their caregivers in the life after stroke and should be recognized and supported by medical professionals and governmental bodies in building up their capacity.
Collaboration between health care professional organisations and patient stroke support organisations needs to be recognized by the EU and National Health authorities leading to the equal access to stroke prevention, management, rehabilitation and improved quality of life after stroke.
This document was approved by stroke experts SAFE, ESO and EBC at Joint Meeting the Chief Medical, Chief Dental and Chief Nursing Officers.
EUROPEAN STROKE ORGANISATION
Urs Fischer MD, MSc
Extraordinarius for Acute Neurology and Stroke
Co-Chairman Stroke Center Bern
Co-Director Clinical Trial Unit Bern
University of Bern, Switzerland
Secretary General European Stroke Organisation
Markku Kaste MD, PhD, FESO, FAHA, FANA
Emeritu Professor of Neurology
University of Helsinki, Finland
Past Chairman of the Department of Neurology
Helsinki University Central Hospital, Finland
Janika Kõrv MD, PhD, FESO
Department of Neurology and Neurosurgery,
University of Tartu, Estonia
STROKE ALLIANCE FOR EUROPE
Jelena Misita, MA, MBA
SAFE Awareness and Advocacy Manager for Europe
London, United Kingdom
EUROPEAN BRAIN COUNCIL
Research Project Manager
Public Health and Policy – Value of Treatment
Please see the signed version of this document here.
Jon Barrick, SAFE’s President since 2014, received an honorary degree of Professional Doctorate in Policy Research and Practice in University of Bath as the recognition of a long and distinguished career serving the public good in the charitable and statutory sectors. (more…)
Despite the fact that obesity increases both the risk for stroke and death, a new study has found that people who are overweight or even mildly obese survive strokes at a higher rate as compared to those with a normal body weight.
The findings, which appear in the Journal of the American Heart Association, adds to the ‘obesity paradox’ seen in previous studies where increased body weight appears to have a protective effect on certain groups of patients.
A stroke occurs when blood flow to an area of the brain is cut off and brain cells are deprived of oxygen and begin to die. Each year about 185,000 people die from a stroke, the fifth leading cause of death in the U.S. and a leading cause of adult disability. (more…)