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Imaging may allow safe tPA treatment of patients with unwitnessed strokes

Imaging may allow safe tPA treatment of patients with unwitnessed strokes

First published on ScienceDaily.com

A study led by Massachusetts General Hospital (MGH) investigators may lead to a significant expansion in the number of stroke patients who can safely be treated with intravenous tPA (tissue plasminogen activator), the “clot busting” drug that has greatly reduced stroke-related disability and deaths in eligible patients. The report, published online in Annals of Neurology, describes the results of a trial using MR-based imaging technologies to identify patients likely to be within 4.5 hours of stroke onset, even though their initial symptoms had not been witnessed. (more…)

Imaging may allow safe tPA treatment of patients with unwitnessed strokes

Dementia trend shows later onset with fewer years of the disease

First published on ScienceDaily.com

The diagnosis is one that a family never wants to hear: Your father has Alzheimer’s disease. Your mother has stroke-related dementia.

A recently released study, included in a special supplement to the Journal of Gerontology, indicates that dementia’s impact might be compressing a bit. That is, people might be developing dementia later and living with it for a shorter period of time. (more…)

Imaging may allow safe tPA treatment of patients with unwitnessed strokes

Compound improves stroke outcome by reducing lingering inflammation

First published on ScienceDaily.com

An experimental compound appears to improve stroke outcome by reducing the destructive inflammation that can continue months after a stroke, scientists report.

Rats consuming compound 21 following a clot-based stroke — the most common type in humans — don’t have a smaller stroke size but do have better memory and movement in its aftermath, says Dr. Adviye Ergul, vascular physiologist and Regents’ Professor in the Department of Physiology at the Medical College of Georgia at Augusta University. (more…)

Imaging may allow safe tPA treatment of patients with unwitnessed strokes

New ‘brain health index’ can predict how well patients will do after stroke

First published on ScienceDaily.com

A new computer programme developed by scientists at the Universities of Edinburgh and Glasgow can assess whole brain deterioration and help predict cognitive function after stroke up to ten times more accurately than current methods.

The new approach, published today in the International Journal of Stroke, can quantify visible brain injury from cerebral small vessel disease (SVD) and brain atrophy by translating the million plus bits of information stored in brain scans into a single measure, the “brain health index.” (more…)

Imaging may allow safe tPA treatment of patients with unwitnessed strokes

Wildfire smoke associated with more ER visits for heart, stroke ailments among seniors

Published first on ScienceDaily

Smoke from wildfires may send people — particularly seniors — to hospital emergency rooms (ERs) with heart, stroke-related complaints, according to new research in the Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

Previous studies have shown that wildfire smoke exacerbates respiratory conditions but yielded inconsistent results for effects on the heart, brain or blood vessels. (more…)