New class of molecules may protect brain from stroke, neurodegenerative diseases

New class of molecules may protect brain from stroke, neurodegenerative diseases

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans, has discovered a new class of molecules in the brain that synchronize cell-to-cell communication and neuroinflammation/immune activity in response to injury or diseases. Elovanoids (ELVs) are bioactive chemical messengers made from omega-3 very long chain polyunsaturated fatty acids (VLC-PUFAs,n-3). They are released on demand when cells are damaged or stressed. (more…)

Make efforts in stroke prevention now to avoid the disabling changes a stroke can cause

Make efforts in stroke prevention now to avoid the disabling changes a stroke can cause

Source: https://worldstrokeorganization.blogspot.com

stroke

Anabela Resende, source: Facebook

Anabela Resende, a survivor of stroke and member of the board of Portugal AVC, shares her stroke experience and reason for preventing strokes.

Where were you when you had your stroke?

I suffered the stroke on January 12, 2013, while I was enjoying a vacation with my husband in the city of Peniche, Portugal.

Could you access a hospital?

I was immediately referred to a hospital.

What expectations did you have for your treatment, rehabilitation, recovery?

At first I did not have great expectations, although I wanted to recover a lot, I was not discouraged, I used to be careful not to create expectations that might not be possible.

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People with AF are at least three times more likely to have a stroke than those without this condition

People with AF are at least three times more likely to have a stroke than those without this condition

New research released on 21st September 2017 by The Economist Intelligence Unit (EIU), a division of The Economist and a leader in global business intelligence, revealed that on average, more than 75 percent of people aged 65 and older worldwide are not being screened for atrial fibrillation (AF) and other common stroke risk factors during routine primary care examinations, even though this population is at high risk for stroke. The EIU “Preventing Stroke: Uneven Progress” report, sponsored by The Bristol-Myers Squibb-Pfizer Alliance, conducted an analysis of 20 countries and found that efforts to screen people for stroke risk factors including AF and hypertension varied widely, even in countries with established health care and developed economies.

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New class of molecules may protect brain from stroke, neurodegenerative diseases

The rat race is over: New livestock model for stroke could speed discovery

It is well-known in the medical field that the pig brain shares certain physiological and anatomical similarities with the human brain. So similar are the two that researchers at the University of Georgia’s Regenerative Bioscience Center have developed the first U.S. pig model for stroke treatments, which will provide essential preclinical data and speed the drug discovery process. (more…)

New class of molecules may protect brain from stroke, neurodegenerative diseases

The importance of the SAFE and ESO Memorandum of Understanding

Two of the most influential bodies in Europe concerning stroke care are the European Stroke Organisation known as ESO, and the Stroke Alliance for Europe, commonly known as SAFE. And these two have joined forces earlier this year to support awareness, prevention and advocacy for improved stroke research and treatments. Stroke patients and those looking after them need to know that they have the safety, choice and empowerment as the guiding principles of care.

Please watch below the interview with Dr. Valeria Caso, neurologist from the University of Perugia, Italy, the President of ESO and John Barrick, the patient advocate and President of the Board of SAFE, the only European-wide alliance of stroke support organisations.
The full-length video is available if you click on the photo. (more…)

New class of molecules may protect brain from stroke, neurodegenerative diseases

Immune cells may heal bleeding brain after strokes

While immune cells called neutrophils are known to act as infantry in the body’s war on germs, a National Institutes of Health-funded study suggests they can act as medics as well. By studying rodents, researchers showed that instead of attacking germs, some neutrophils may help heal the brain after an intracerebral hemorrhage, a form of stroke caused by ruptured blood vessels. The study suggests that two neutrophil-related proteins may play critical roles in protecting the brain from stroke-induced damage and could be used as treatments for intracerebral hemorrhage.

“Intracerebral hemorrhage is a damaging and often fatal form of stroke for which there are no effective medicines,” said Jaroslaw Aronowski, M.D., Ph.D., professor, department of neurology, at the University of Texas Health Science Center at Houston, and senior author of the study published in Nature Communications. “Our results are a hopeful first step towards developing a treatment for this devastating form of stroke.” (more…)

Action on Stroke – Live Webinar 2017: Wednesday, 21st September 2017

Action on Stroke – Live Webinar 2017: Wednesday, 21st September 2017

The Economist Events and sponsor The Bristol-Myers Squibb and Pfizer Alliance hosted a webinar “Action on Stroke”, on September 21st 10:00 am EST/3:00 pm GMT, to address policy approaches to stroke prevention.

With heart disease and stroke as some of the leading causes of death worldwide, understanding the opportunity for policy to facilitate prevention is paramount.

– As there is a predicted increase in stroke incidence until 2030 in Europe and other parts of the world (Burden of Stroke Report and Global Burden of Disease Study) policy efforts on stroke prevention have to be increased (and SAFE as the patient voice in Europe is advocating for a better stroke prevention on the European level). –  said Dr Markus Wagner, SAFE Vice President and one of the panelists at Action on Stroke – Live Webinar 2017 which happened on Wednesday, September 21st in London.

Please watch the entire webinar below:

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New class of molecules may protect brain from stroke, neurodegenerative diseases

Determining motor deficits more precisely following a stroke

After a stroke, many people are unable to successfully perform basic hand movements in everyday life. The reason are symptoms of hemiparesis resulting from damage to the brain. These very frequently affect fine motor skills. A team from the Technical University of Munich (TUM) is now paving the way to better diagnosis and more targeted therapy. (more…)

New class of molecules may protect brain from stroke, neurodegenerative diseases

New mindset in the search for stroke therapies

UNSW researchers have identified a promising new avenue to explore in the search for stroke treatments, after translating findings from Alzheimer’s disease.

The study published in Nature Communications finds that mice deficient in tau, a protein within brain cells (neurons), are significantly protected from excitotoxic brain damage after experimental stroke. (more…)

New class of molecules may protect brain from stroke, neurodegenerative diseases

Seven steps to keep your brain healthy from childhood to old age

A healthy lifestyle benefits your brain as much as the rest of your body — and may lessen the risk of cognitive decline (a loss of the ability to think well) as you age, according to a new advisory from the American Heart Association/American Stroke Association.

Both the heart and brain need adequate blood flow, but in many people, blood vessels slowly become narrowed or blocked over the course of their life, a disease process known as atherosclerosis, the cause of many heart attacks and strokes. Many risk factors for atherosclerosis can be modified by following a healthy diet, getting enough physical activity, avoiding tobacco products and other strategies. (more…)