UMBRELLA: Using AI to improve stroke care 

UMBRELLA: Using AI to improve stroke care 

On Brain Awareness Week’s third day we are focusing on UMBRELLA, a European research project that uses artificial intelligence (AI) and digital tools to improve how strokes are diagnosed, treated and managed. 

A stroke occurs when blood flow to the brain is blocked or a blood vessel bursts. Quick treatment is vital, but recovery can be long and complex and many survivors remain at risk of another stroke.

UMBRELLA aims to support doctors by using AI to help them make faster and more personalised decisions, while keeping patient information safe and private.

The project follows a careful process: health data is securely collected, organised and analysed inside hospitals. Personal details are removed, and strict privacy rules are followed. The AI is then trained to recognise patterns and tested to make sure it works safely and truly helps patient care. 

Led by Vall d’Hebron Research Institute and Siemens Healthineers, and supported by the EU’s Innovative Health Initiative, the project brings together hospitals, researchers, patient organisations and companies from across Europe. 

“Stroke survivors live with many long-term challenges. Better tools to support them are urgently needed. UMBRELLA is an exciting step toward more personalised and effective stroke care, with the potential to make a real difference for patients and families across Europe,” said Arlene Wilkie, Director General of SAFE. 

By improving diagnosis, treatment and prevention, UMBRELLA aims to transform stroke care and improve the quality of lives of thousands of people. 

To learn more about the project: 

Visit the Umbrella website https://umbrella-ihi.eu
Or contact research@safestroke.eu 

This project is supported by the Innovative Health Initiative Joint Undertaking (IHI JU) under grant agreement No 101172825. The JU receives support from the European Union’s Horizon Europe research and innovation programme and COCIR, EFPIA, Europa Bío, MedTech Europe and Vaccines Europe.

EAST-STROKE: Study to prevent second strokes by treating irregular heartbeat

EAST-STROKE: Study to prevent second strokes by treating irregular heartbeat

EAST-STROKE is a European study that is exploring whether treating an irregular heartbeat earlier after a stroke could help prevent second strokes. 

Atrial fibrillation (AF), a condition where the heart beats unevenly and sometimes too fast. This can lead to blood clots forming in the heart, which in turn may travel to the brain and cause stroke. Doctors usually treat these patients with blood-thinning medicines and drugs to slow the heart rate down.  

EAST-STROKE will test whether adding an additional treatment to restore a normal heart rhythm, (rhythm control) soon after a stroke can further reduce the risk of future strokes and heart problems. 

Rhythm control may include additional medications or a procedure called ablation, where doctors carefully treat small areas of heart tissue that are causing the irregular rhythm. The goal with this treatment would be to help the heart beat normally again. 

Many stroke survivors are left with long-term disabilities following a stroke. For those who also have atrial fibrillation (AF), the risk of having another stroke is high. 

“Life after stroke can be a long and difficult journey. By treating the heart rhythm problem early, we hope to reduce the risk of further strokes and help stroke survivors avoid more complications that affect their daily lives.” said Dr Märit Jensen, Neurologist at University Medical Center Hamburg-Eppendorf. 

The study will include 1,746 patients in multiple countries and is funded by the European Union.  

Arlene Wilkie, Director General of the Stroke Alliance for Europe (SAFE), said: “If this treatment approach proves safe and effective, it would change how we care for stroke patients with atrial fibrillation and could help prevent many future strokes.” 

If successful, the EAST-STROKE trial could lead to a major shift in stroke treatment, helping thousands of patients worldwide avoid recurrent strokes and heart complications. 

For more information, see video: https://youtu.be/JM7wKqkCEYk 

Or visit the EAST-STROKE website: https://east-stroke.eu

Funded by the EU

The project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement number 101156541 

POC4Triage: European hospitals working together to improve emergency stroke diagnosis 

POC4Triage: European hospitals working together to improve emergency stroke diagnosis 

When someone has a stroke, every minute counts. Quick and accurate diagnosis is critical to ensure patients receive the right treatment as soon as possible. 

The POC4Triage project brings together hospitals, researchers and patient organisations across Europe to test four portable devices in real emergency settings, from ambulances to hospital emergency departments. By running the study in multiple countries, researchers can see how these tools perform in different healthcare systems and diverse groups of patients. 

At Amsterdam UMC (Netherlands) and Vall d’Hebron Hospital (Spain), researchers are evaluating two brain-monitoring devices: 

  • A lightweight electroencephaloeraphy (EEG) patch placed just below the hairline to measure brain activity 
  • A functional near-infrared spectroscopy (fNIRS) device that uses harmless light to monitor blood flow in the brain 

The devices are tested in stages, first with healthy volunteers, then in emergency departments and finally in ambulances. This stepwise approach allows teams to improve the technology before it is used in urgent care. 

Patients who take part may not benefit directly during their own emergency, but their involvement is vital. By contributing to research, they help doctors understand how to recognise stroke earlier and diagnose more accurately. In the future, this could lead to faster treatment and better recovery for stroke patients across Europe.

Arlene Wilkie, Director General at Stroke Alliance for Europe says: 

“POC4Triage shows how research in real emergency settings can lead to devices that improve stroke care. Time is brain, every improvement in speed and accuracy has the potential to save lives, reduce disability and quality of life for survivors in the future.” 

For more information 

POC4Triage has received funding from the European Union under grant agreement No 101137358. 

Launch of the MEP Cardiovascular Health Group

Launch of the MEP Cardiovascular Health Group

SAFE was pleased to attend the launch of the new MEP Cardiovascular Health Group at the European Parliament in Brussels. Chaired by MEP Romana Jerković (S&D, Croatia), the group met with around 50 delegates from the European Alliance for Cardiovascular Health to discuss the year’s work programme and to mark the launch of a new publication by the Alliance: “A European Cardiovascular Health Plan: The Roadmap.” 

Representing SAFE at the event were Arlene Wilkie, our Director General, alongside Liliana Curea from ALIA, Romania, and Adam Siger from Fundacja Udaru Mózgu, Poland. The formation of this dedicated group within the European Parliament represents a significant step forward in driving coordinated EU action to improve cardiovascular health outcomes across member states.

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SAFE at the EACH Cardiovascular Health Summit 2025

SAFE at the EACH Cardiovascular Health Summit 2025

The EACH Cardiovascular Health Summit 2025 in Brussels brought together policymakers, clinicians, researchers and patient advocates to address Europe’s biggest health challenge: cardiovascular disease.
The event focused on tackling inequalities, improving prevention and early detection, and strengthening patient‑centred care across Europe. A major highlight was the official launch of the EU Cardiovascular Health Plan by the European Health Commissioner, marking a historic step forward for cardiovascular health across the EU.
SAFE was represented by Arlene Wilkie, alongside SAFE members Marina Charalambous (Cyprus), Diana Wong-Ramos (Portugal), Adam Siger (Poland) and Dorina Dobreva (Bulgaria). Arlene participated in a high‑level panel discussion where she welcomed the new Plan but urged the community to ensure that stroke is not left behind, emphasising the need for integrated action across all cardiovascular conditions. Diana also took part in a panel discussion where she highlighted the importance of reducing inequalities across Europe and stressed how coordinated EU‑level action can help close persistent gaps in cardiovascular outcomes.